Independent 3rd party lab testing reveals 80% of popular nattokinase brands FAILED potency testing. Only 1 out of 5 brands actually delivered what they promised.
According to independent SORA Labs testing of 5 popular brands, Natural Foundation Supplements is the best nattokinase supplement because:
We sent 5 popular Amazon nattokinase supplements to SORA Laboratories for independent potency testing using High-Performance Liquid Chromatography (HPLC) and spectrophotometric analysis. The results were shocking - 4 out of 5 brands failed to meet their own label claims.
| Product | Rating | Dosage (FU) | Analysis | Results |
|---|---|---|---|---|
|
★★★★★ 4.9/5 | 5000 FU (Verified >6720 FU) | 3rd Party Lab Verified | 🏆SORA Labs Winner |
|
★★★☆☆ 3.2/5 | 4000 FU (Actual: 3720 FU) | Underdosed Formula | Budget Option |
|
★★☆☆☆ 2.8/5 | 4000 FU (Actual: <2680 FU) | Severely Underdosed | Avoid |
|
★★☆☆☆ 2.9/5 | 4000 FU (Actual: 2800 FU) | Failed Lab Testing | Not Recommended |
|
★★☆☆☆ 2.5/5 | 4000 FU (Actual: <2660 FU) | Worst Lab Results | Avoid |
Medically Reviewed: This content has been reviewed by licensed healthcare professionals specializing in cardiovascular health and clinical pharmacology. Our testing methodology follows established pharmaceutical industry standards for supplement quality assessment.
Why you can trust these results.
Unlike other supplement review sites that rely on marketing claims and user reviews, we invested over $2,000 in independent 3rd party laboratory testing to give you the truth about nattokinase supplements. Here's exactly how we conducted our investigation.
Why SORA Labs: We chose SORA Laboratories because they are ISO/IEC 17025:2017 accredited - the international standard for testing and calibration laboratories. With over 20 years of experience and FDA cGMP compliance, SORA Labs specializes in enzyme assays and is recognized as the foremost expert in testing natural ingredient potency.
SORA Labs utilizes High-Performance Liquid Chromatography (HPLC) and spectrophotometric analysis following United States Pharmacopeia (USP) guidelines for nattokinase potency verification.
How We Chose Brands: We selected the 5 most popular nattokinase supplements on Amazon based on sales volume, review count, and marketing claims. We purchased each product directly from Amazon using normal consumer channels to ensure we tested exactly what you would receive.
Scientific Standards: SORA Labs used validated methodologies from compendial sources including USP (United States Pharmacopeia) and British Pharmacopeia. Each sample underwent rigorous testing protocols:
Controlled Environment: All samples were stored and tested under controlled laboratory conditions at 25.3°C to ensure accurate results. Each lot was identified and tracked with specific lot numbers to ensure traceability and reproducibility of results.
What We Measured: The critical metric for nattokinase effectiveness is Fibrinolytic Units (FU) - this measures the enzyme's ability to break down fibrin clots. We compared each product's actual FU content against their label claims to determine potency accuracy.
Full Documentation: We maintain complete certificates of analysis for each tested product with SORA Labs reference numbers. This isn't marketing - these are real lab results that can be independently verified.
Internationally recognized standard for testing and calibration laboratories, ensuring the highest level of accuracy and reliability.
Full compliance with FDA current Good Manufacturing Practice regulations for the nutritional supplement industry.
Over two decades of specialization in analytical testing, with particular expertise in enzyme assays and natural ingredients.
Recognized as the leading experts in testing enzyme quality and potency in natural ingredient raw materials and finished products.
Our nattokinase reviews are based exclusively on objective laboratory data, not subjective opinions or marketing claims. Each product evaluation considers:
Editorial Independence: Our reviews and rankings are based solely on laboratory test results and objective analysis. We are not paid by supplement companies to influence our reviews or rankings.
Partnerships Disclosure: This site is supported through partnerships with verified supplement retailers. Our lab testing and reviews remain independent regardless of commercial relationships.
Medical Disclaimer: The information on this website is for educational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Always consult with a healthcare provider before starting any supplement regimen.
Most supplement review sites simply repeat marketing claims or rely on user reviews. We believed consumers deserved better. By investing in professional laboratory testing, we uncovered the shocking truth: 80% of popular nattokinase brands don't deliver what they promise.
This investment ensures you get factual, science-based information to make informed decisions about your cardiovascular health - not marketing hype.
Nattokinase has been studied in clinical trials and laboratory research. Below are key, correctly cited findings and the exact study links.
Key Finding: In a randomized, placebo-controlled trial, 73 adults took nattokinase (2000 FU/day) for 8 weeks and saw mean reductions of about −5.5 mmHg systolic and −2.8 mmHg diastolic vs placebo.
"Nattokinase produced modest but significant BP reductions over 8 weeks."
Key Finding: In a double-blind crossover study (n=12), a single 2000 FU dose increased D-dimer and fibrin/fibrinogen degradation products and prolonged aPTT at 2–8 hours; Factor VIII activity decreased at 4–6 hours.
"Findings support short-term enhancement of fibrinolysis/anticoagulation after oral NK."
Key Finding: Open-label, self-controlled trial (n=45): ~4000 FU/day for 2 months lowered fibrinogen (~9%), Factor VII (~14%), and Factor VIII (~17%); lipids were unchanged. No notable adverse events were reported.
"Suggests NK can reduce select coagulation factors; controlled trials are needed for confirmation."
Key Finding: Retrospective cohort (n=1,062): 10,800 FU/day for 12 months reduced CCA-IMT (~22%) and carotid plaque area (~36%) and improved TC/LDL/TG; 3,600 FU/day showed no effect.
"Higher daily doses were associated with improvements in atherosclerosis and lipids; causal inference limited by non-randomized design."
The ONLY brand that passed 3rd party lab testing - exceeded label claims by 34%+
Lab Reference #35260854: Natural Foundation Supplements is the ONLY nattokinase supplement that passed independent 3rd party testing by SORA Labs. While claiming 5000 FU per capsule, lab testing revealed it actually contains over 6,720 FU - exceeding its label claim by more than 34%.
Bottom Line: If you want a nattokinase supplement that actually delivers what it promises, Natural Foundation Supplements is your only proven choice. While 80% of popular brands failed lab testing, this is the one that exceeded expectations.
Get Lab-Verified Nattokinase →Missing 280 FU units per serving - failed SORA Labs testing
Lab Reference #35170634: SORA Labs testing revealed that Horbaach Nattokinase contains only 3,720 FU per 2 capsules, despite claiming 4,000 FU. You're missing 280 FU units per serving - that's 7% less nattokinase than you're paying for.
Bottom Line: While cheaper upfront, Horbaach's underdosed formula means you're not getting the cardiovascular benefits you're seeking. Why gamble with your health when lab-verified options exist?
See Lab-Verified Alternative →Missing over 1,320 FU units - only 67% of claimed potency
Lab Reference #35170661: SORA Labs testing exposed Bulk Supplements as severely underdosed, containing less than 2,680 FU per capsule while claiming 4,000 FU. You're getting less than 67% of what you're paying for - that's over 1,320 missing FU units per capsule.
Bottom Line: Bulk Supplements failed laboratory testing spectacularly. With less than 67% of claimed potency, this supplement is a waste of money and won't provide the cardiovascular support you need. Avoid at all costs.
Get Lab-Verified Alternative →Missing 1,200 FU units per serving - failed SORA Labs testing
Lab Reference #35170626: SORA Labs testing revealed Double Wood Nattokinase contains only 2,800 FU per 2 capsules, despite claiming 4,000 FU. That's a massive 1,200 FU shortfall - 30% less nattokinase than advertised.
Bottom Line: Double Wood's massive 30% potency shortfall makes it unsuitable for serious cardiovascular support. Why settle for 70% of what you need when lab-verified alternatives exist?
Get Lab-Verified Alternative →The worst performer - largest capsules, lowest potency, missing 1,340+ FU
Lab Reference #35170642: Luma Nutrition was the worst performer in SORA Labs testing. Despite having the largest capsules (1,038.6 mg per 2 capsules), it delivered less than 2,660 FU while claiming 4,000 FU. Capsule size means nothing without proper potency.
Bottom Line: Luma Nutrition proves that bigger capsules don't mean better results. With the worst lab test results and missing over 33% of promised potency, this is the supplement to avoid at all costs.
Get Lab-Verified Alternative →Common questions about nattokinase supplements and our lab testing results.